Wahi a kahi hui noiʻi hui mai Harvard Medical School (HMS) a me MIT General Hospital, ua hoʻokō lākou i ka hoʻoponopono ʻana i ka hopena o kahi laser microdisk me ka hoʻohana ʻana i ke ʻano PEC etching, e hana i kahi kumu hou no ka nanophotonics a me ka biomedicine "promising."
(Hiki ke hoʻoponopono ʻia ka hopena o ka laser microdisk e ke ʻano PEC etching)
Ma na kula onanophotonicsa me ka biomedicine, microdisknā lasersa ua lilo nā lasers nanodisk i mea hoʻohikinā kumu māmāa me nā ʻimi. Ma kekahi mau noi e like me ke kamaʻilio photonic on-chip, bioimaging on-chip, biochemical sensing, a me quantum photon information processing, pono lākou e hoʻokō i ka hopena laser i ka hoʻoholo ʻana i ka lōʻihi o ka nalu a me ka pololei o ka band narrow. Eia nō naʻe, ke paʻakikī nei ka hana ʻana i nā lasers microdisk a me nanodisk o kēia lōʻihi hawewe pololei ma ke ʻano nui. ʻO nā kaʻina hana nanofabrication o kēia manawa e hoʻolauna i ka randomness o ka disc diameter, kahi mea paʻakikī ke loaʻa i kahi lōʻihi i hoʻonohonoho ʻia i ka hoʻoili ʻana a me ka hana ʻana o ka laser.Laau OptoelectronicUa hoʻomohala ʻo ia i kahi ʻenehana etching optochemical (PEC) hou e kōkua i ka hoʻoponopono pololei ʻana i ka lōʻihi hawewe laser o kahi laser microdisk me ka pololei subnanometer. Ua paʻi ʻia ka hana ma ka puke pai Advanced Photonics.
kiʻi kiʻimika
Wahi a nā hōʻike, hiki i ke ʻano hou o ka hui ke hana i nā lasers micro-disk a me nā arrays laser nanodisk me nā lōʻihi hawewe hoʻokuʻu i koho mua ʻia. ʻO ke kī i kēia holomua ʻo ka hoʻohana ʻana i ka PEC etching, e hāʻawi ana i kahi ala kūpono a hiki ke hoʻopaʻa ʻia e hoʻoponopono i ka lōʻihi o ka nalu o kahi laser microdisc. Ma nā hualoaʻa i luna, ua loaʻa i ka hui ka indium Gallium arsenide phosphating microdisks i uhi ʻia me ka silica ma ke kahua kolamu indium phosphide. A laila hoʻokani pololei lākou i ka lōʻihi hawewe laser o kēia mau microdisks i kahi waiwai i hoʻoholo ʻia ma o ka hana ʻana i ke kiʻi kiʻi kiʻi i loko o kahi hopena diluted o sulfuric acid.
Ua noiʻi pū lākou i nā hana a me ka hoʻoikaika o nā kiʻi kiʻi kiʻi kūikawā (PEC). ʻO ka hope, ua hoʻololi lākou i ka microdisk i hoʻopaʻa ʻia i ka lōʻihi hawewe ma luna o kahi substrate polydimethylsiloxane e hana ai i nā ʻāpana laser kūʻokoʻa me nā lōʻihi hawewe laser ʻokoʻa. Hōʻike ka microdisk i kahi bandwidth ultra-wideband o ka hoʻokuʻu ʻana i ka laser, me kalaserma ke kolamu i emi iho ma mua o 0.6 nm a me ka mea kaawale ma lalo o 1.5 nm.
Wehe i ka puka i nā noi biomedical
ʻO kēia hopena e wehe i ka puka i nā nanophotonics hou a me nā noi biomedical. No ka laʻana, hiki i nā lasers microdisk kū hoʻokahi ke lawelawe ma ke ʻano he physico-optical barcodes no nā heterogeneous biological samples, e hiki ai ke hoʻopaʻa inoa ʻana i nā ʻano cell specific a me ka huli ʻana o nā molekole kikoʻī i ka loiloi multiplex. e like me nā fluorophores organik, nā kiko kuantum, a me nā peʻa fluorescent, nona nā laina laina ākea ākea. No laila, hiki ke hoʻopaʻa inoa ʻia kekahi mau ʻano kelepona kikoʻī i ka manawa like. ʻO ka ʻokoʻa, hiki i ka ultra-narrow band light emission o kahi microdisk laser ke ʻike i nā ʻano cell hou aku i ka manawa like.
Ua hoʻāʻo a hōʻike maikaʻi ka hui i nā ʻāpana laser microdisk i hoʻopaʻa pono ʻia ma ke ʻano he biomarkers, me ka hoʻohana ʻana iā lākou e hoʻopaʻa inoa i nā cell epithelial breast maʻamau MCF10A. Me kā lākou ultra-wideband emission, hiki i kēia mau lasers ke hoʻololi i ka biosensing, me ka hoʻohana ʻana i nā ʻenehana biomedical a me ka optical e like me ka cytodynamic imaging, flow cytometry, a me ka loiloi multi-omics. ʻO ka ʻenehana e pili ana i ka PEC etching e hōʻailona i kahi holomua nui i nā lasers microdisk. ʻO ka scalability o ke ʻano, a me kāna subnanometer precision, e wehe i nā mea hou no ka helu ʻana i nā noi o nā lasers i nā nanophotonics a me nā mea biomedical, a me nā barcodes no nā heluna cell kikoʻī a me nā molekele analytical.
Ka manawa hoʻouna: Jan-29-2024