Nā loina o ke kiʻi photoacoustic

Nā loina o ke kiʻi photoacoustic

ʻO ke Kiʻi Photoacoustic (PAI) kahi ʻenehana kiʻi lapaʻau e hoʻohui pū ana i nānā makaa me nā acoustics e hana i nā hōʻailona ultrasonic me ka hoʻohana ʻana i ka launa pū ʻana omālamalamame nā ʻiʻo e kiʻi i nā kiʻi ʻiʻo hoʻonā kiʻekiʻe. Hoʻohana nui ʻia ia i nā kahua biomedical, ʻoi aku hoʻi i ka ʻike ʻana i ka puʻupuʻu, ke kiʻi ʻana o nā vascular, ke kiʻi ʻana i ka ʻili a me nā kahua ʻē aʻe.

Kumumanaʻo:
1. Ka omo ʻana o ka mālamalama a me ka hoʻonui ʻana o ka wela: – Hoʻohana ke kiʻi photoacoustic i ka hopena wela i hana ʻia e ka omo ʻana o ka mālamalama. Hoʻopili nā molekala pigment i loko o nā ʻiʻo (e laʻa, hemoglobin, melanin) i nā photons (maʻamau ka mālamalama kokoke i ka infrared), kahi i hoʻololi ʻia i ikehu wela, e hoʻonui ai i ka mahana kūloko.
2. ʻO ka hoʻonui wela ke kumu o ka ultrasound: – ʻO ka piʻi ʻana o ka mahana e alakaʻi ai i ka hoʻonui wela liʻiliʻi o ke kino, kahi e hoʻopuka ai i nā nalu kaomi (ʻo ia hoʻi ka ultrasound).
3. ʻIke ʻana i ka ultrasonic: – Hoʻolaha nā nalu ultrasonic i hana ʻia i loko o nā ʻiʻo, a loaʻa a hoʻopaʻa ʻia kēia mau hōʻailona e nā mea ʻike ultrasonic (e like me nā probes ultrasonic).
4. Ke kūkulu hou ʻana i ke kiʻi: ua helu ʻia a hana ʻia ka hōʻailona ultrasonic i hōʻiliʻili ʻia e kūkulu hou i ke kiʻi o ke ʻano a me ka hana o ka ʻiʻo, hiki ke hāʻawi i nā ʻano omo optical o ka ʻiʻo. Nā pono o ke kiʻi photoacoustic: ʻOkoʻa kiʻekiʻe: Hilinaʻi ke kiʻi photoacoustic i nā ʻano omo mālamalama o nā ʻiʻo, a ʻo nā ʻiʻo like ʻole (e like me ke koko, ka momona, nā ʻiʻo, a me nā mea ʻē aʻe) he mau hiki like ʻole ke omo i ka mālamalama, no laila hiki iā ia ke hāʻawi i nā kiʻi ʻokoʻa kiʻekiʻe. Hoʻonā kiʻekiʻe: Ma ka hoʻohana ʻana i ka hoʻonā spatial kiʻekiʻe o ka ultrasound, hiki i ke kiʻi photoacoustic ke hoʻokō i ka pololei o ke kiʻi millimeter a i ʻole sub-millimeter. ʻAʻole invasive: ʻAʻole invasive ke kiʻi photoacoustic, ʻaʻole e hōʻino ka mālamalama a me ke kani i nā ʻiʻo, kūpono loa no ka ʻike lapaʻau kanaka. Ka hiki ke kiʻi hohonu: Ke hoʻohālikelike ʻia me ke kiʻi optical kuʻuna, hiki i ke kiʻi photoacoustic ke komo i kekahi mau kenimika ma lalo o ka ʻili, kūpono no ke kiʻi ʻiʻo hohonu.

Noi:
1. Kiʻi vascular: - Hiki i ke kiʻi photoacoustic ke ʻike i nā waiwai omo kukui o ka hemoglobin i loko o ke koko, no laila hiki iā ia ke hōʻike pololei i ke ʻano a me ke kūlana oxygenation o nā kīʻaha koko no ka nānā ʻana i ka microcirculation a me ka hoʻoholo ʻana i nā maʻi.
2. Ka ʻike ʻana i ka puʻupuʻu: - ʻO ka angiogenesis i loko o nā ʻiʻo puʻupuʻu he nui loa ia, a hiki i ke kiʻi photoacoustic ke kōkua i ka ʻike mua ʻana i nā puʻupuʻu ma ka ʻike ʻana i nā ʻano ʻē i ke ʻano o nā kīʻaha koko.
3. Kiʻi hana: - Hiki i ke kiʻi photoacoustic ke loiloi i ka lako oxygen o nā ʻiʻo ma ka ʻike ʻana i ka nui o ka oxygenation a me ka deoxyhemoglobin i loko o nā ʻiʻo, he mea nui ia no ka nānā ʻana i nā hana o nā maʻi e like me ke kanesa a me nā maʻi cardiovascular.
4. Kiʻi ʻili: – No ka mea, he ʻano koʻikoʻi loa ke kiʻi photoacoustic i nā ʻiʻo ma luna o ka ʻili, kūpono ia no ka ʻike mua ʻana i ka maʻi ʻili a me ka nānā ʻana i nā ʻano ʻē o ka ʻili.
5. Kiʻi lolo: Hiki i ke kiʻi photoacoustic ke loaʻa ka ʻike kahe koko o ka lolo ma ke ʻano ʻaʻole invasive no ke aʻo ʻana i nā maʻi lolo e like me ka hahau ʻana a me ka maʻi epilepsy.

Nā pilikia a me nā kuhikuhi hoʻomohala o ke kiʻi photoacoustic:
Kumu kukuikoho: He ʻokoʻa ke komo ʻana o ka mālamalama i nā nalu like ʻole, pehea e koho ai i ka hoʻonā kaulike nalu kūpono a me ka hohonu o ke komo ʻana he paʻakikī. Ka hana ʻana i nā hōʻailona: ʻO ka loaʻa ʻana a me ka hana ʻana i nā hōʻailona ultrasonic e pono ai nā algorithms wikiwiki a pololei, a he mea nui nō hoʻi ka hoʻomohala ʻana i ka ʻenehana hana hou kiʻi. Kiʻi Multimodal: Hiki ke hoʻohui ʻia ke kiʻi Photoacoustic me nā ʻano kiʻi ʻē aʻe (e like me MRI, CT, ultrasound imaging) e hāʻawi i ka ʻike biomedical piha.

He ʻenehana kiʻi biomedical hou a multi-functional ka kiʻi photoacoustic, nona nā ʻano o ke ʻano ʻokoʻa kiʻekiʻe, ka hoʻonā kiʻekiʻe a me ka non-invasive. Me ka hoʻomohala ʻana o ka ʻenehana, ua loaʻa i ka kiʻi photoacoustic nā manaʻolana ākea no ka hoʻohana ʻana i ka ʻike lapaʻau, ka noiʻi biology kumu, ka hoʻomohala ʻana i nā lāʻau lapaʻau a me nā ʻoihana ʻē aʻe.